Microbial Fermentation Defoamer Solution - Customized by Chemi Tech

Excessive foam in microbial fermentation is a common issue that severely impacts production efficiency. It reduces effective fermenter volume, lowers oxygen transfer rates, and may cause broth overflow or contamination, leading to product loss. Traditional defoamers often require high dosage and can negatively affect cell growth or product synthesis.  

To address these challenges, Chemi Tech has developed a series of high-performance defoamers specifically for microbial fermentation. Our solutions are based on deep process understanding and delivered through a structured approach:  

Step 1: Problem Diagnosis & Sample Analysis  

Our technical team works closely with clients to understand their fermentation process, microbial strain, foaming causes, and current defoaming strategies, providing tailored samples for testing.  

Step 2: Customized Formulation Design  

We adjust defoamer compatibility, spreading ability, and persistence according to fermentation types (e.g., antibiotics, enzymes, organic acids) to ensure rapid foam collapse at low dosage without affecting metabolism.  

Step 3: Process Integration & Optimization  

We advise on injection points, methods, and concentrations to avoid overuse and facilitate downstream purification.  

Case Study:  

A biotech company struggled with intense foam peaks during late fermentation, requiring manual defoamer addition and resulting in inconsistent product yield. After switching to Chemi Tech defoamer CP-12 with automated feeding control, foam level stabilized within safe range, fermentation consistency improved, and downstream costs reduced.  

Chemi Tech defoamers offer long-lasting foam suppression, excellent compatibility, and non-toxicity to microorganisms, suitable for both aerobic and anaerobic systems. We are committed to supporting stable and efficient fermentation through innovative solutions.