In fermentation production, excessive foam is a common and troublesome problem. Excessive foam not only reduces the effective volume of the fermentation tank, but may also cause broth overflow, increasing the risk of contamination; in severe cases it even forces production to be interrupted, resulting in wasted raw materials and rising costs. Traditional defoaming methods often have only a short-lived effect or may affect the activity of the microbial strain, making it difficult to achieve stable control at the root.
To address these core pain points, Chemi Tech, drawing on deep technical accumulation, has developed a series of high-efficiency fermentation defoamers. Our solution is not a simple addition of chemicals, but is based on an in-depth understanding of the fermentation system and the causes of foam. The products use specially modified polysiloxanes and composite synergistic ingredients, offering the dual efficacy of rapid foam breaking and lasting foam suppression. Their excellent dispersibility and compatibility ensure uniform action within the fermentation system, while not affecting the biosynthetic pathway of the target product or the subsequent extraction process.
Our professional service steps are clear and definite: first, the technical team will learn in detail about the customer's fermentation process parameters, medium composition, and foam characteristics. Then, through laboratory simulation and evaluation, we screen and recommend the most suitable defoamer model and addition scheme. We provide precise guidance on the dosing point and dosage to ensure the defoamer delivers maximum efficacy at the critical moment, avoiding blind use. Finally, we support on-site application follow-up, making fine adjustments based on actual production feedback, to achieve the best defoaming economics and process stability.
For example, an enterprise focused on the production of bio-based chemicals, in one of its amino acid fermentation projects, experienced a sharp increase in foam in the middle and late stages; the conventional defoamer had a short foam-suppression time, required frequent replenishment, and slightly inhibited the acid production rate. After adopting the Chemi Tech customized defoamer, a single addition covered the entire peak foaming period, extending the foam-suppression time by about 50% and effectively controlling the risk of broth overflow. More importantly, under stable process conditions, the final fermentation titer of the target product maintained its original high level, proving the product's good biocompatibility. The customer therefore reduced the total amount of defoamer used and the operating frequency, improving production continuity and economic efficiency.
Choosing Chemi Tech means choosing reliable process assurance. Through precise defoaming solutions, we are committed to helping customers optimize fermentation processes, improve equipment utilization, and ensure production safety and stable product quality, ultimately achieving the goal of cost reduction and efficiency improvement.