In fermentation production processes, uncontrolled foam is a thorny problem that has long troubled many producers. A large amount of foam not only reduces the effective fermentation volume, causing a waste of capacity, but may also trigger liquid overflow, increasing the equipment cleaning burden and the risk of contamination, ultimately affecting product yield and quality consistency.
Common defoaming methods on the market are often short-lived, require frequent addition, or may adversely affect strain activity and subsequent processes. Achieving durable, efficient, and safe defoaming is a key pain point in improving the economic benefits of fermentation.
Drawing on an in-depth understanding of fermentation processes, Chemi Tech has developed a series of dedicated fermentation defoamers. The core of our solution lies in targeted design: first, the product has excellent instant foam-breaking and long-lasting foam-inhibiting capabilities, quickly eliminating already-generated foam and inhibiting foam regeneration over the long term. Second, its good dispersibility and compatibility ensure it works stably in the fermentation system without affecting dissolved oxygen transfer or normal cell metabolism. Finally, the product has been carefully screened and causes no adverse interference with the separation and purification of the target product.
The specific implementation steps are divided into four: the first step is problem diagnosis and technical communication. Our engineers will gain a detailed understanding of your fermentation process, strain characteristics, and the points where foam is generated. The second step is screening and laboratory evaluation. We provide suitable defoamer samples and verify their defoaming and foam-inhibiting effects and their impact on the process under simulated or small-scale trial conditions. The third step is pilot testing and determining the application plan. In scale-up trials, we optimize the dosing point, method, and dosage to form a standardized operating procedure. The fourth step is large-scale supply and continuous tracking. We provide a stable product supply and make regular follow-up visits to ensure stable long-term results.
We once served a biotechnology enterprise whose amino acid fermentation project often experienced a surge in foam in the middle and late stages; the original defoamer was ineffective and affected the extraction yield. By applying Chemi Tech's customized defoaming solution, the defoamer dosage was reduced by about 30%, the fermentation tank filling coefficient increased by 8%, and the extraction efficiency of the target product was improved, with significantly enhanced production stability.
Choosing Chemi Tech is not just choosing a product but choosing a reliable process partner. Through professional products and technical services, we are committed to helping customers overcome fermentation defoaming challenges, unlock production potential, and achieve cost reduction and efficiency improvement.